“The object recognition test is like cognitive recognition tests in humans, where you are shown a series of images, then have to remember which ones you’ve seen before after some time passes,” Thaiss said. “And the maze test is like people trying to recall where they parked their car at a large shopping center. What these tasks have in common, in mice and in people, is that they are very strongly dependent on activity in the hippocampus, because that is where memories are encoded.”
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